24kHz400 watts400W ultrasoundautomatic data recordingflow cellhigh power ultrasoundlab devicelab samplespowerful ultrasonic processorprobe-typeprobe-type ultrasonicatorssample preparationsample protocollingSD card data recordingSD-cardsonotrodetissue homogenizertissue homogenizerstouch displaytouch screenultrasonic flow cellultrasonic lab devicesUP400SUP400St
With the UP400St (400W, 24kHz), the serial of Hielscher digital sonicators is expanded by a powerful 400 watts ultrasonic probe-type homogenizer. The new UP400St is the successor of UP400S – one of the most popular lab sonicators. Its high ultrasound power and robustness make the UP400St perfectly suitable for the use in demanding environments. Equipped with a colored touch screen for easy controllability, integrated LEDs for sample illumination, pluggable temperature sensor, integrated SD-Card for automatic data recording, as well as many other features, the UP400St convinces by its user-friendliness and reliability. The UP400St is ideal for efficient and precise sonication of larger samples.
Being our most powerful laboratory device, the UP400St is suitable to fulfill various applications such as homogenizing, emulsifying, dispersing, deagglomeration & wet-milling (particle size reduction), cell disruption & disintegration, extraction, degassing, as well as sonochemical processes. With sonotrodes of a diameter range from 3 to 40mm, the device is suited for the sonication of sample volumes from 5 to 4000ml. In combination with a flow cell approx. 10 to 50 liters per hour can be sonicated. When used for sample preparation, the UP400St is mainly used for bigger volumes. It is suited for the development of ultrasonic applications in the laboratory, but also in the bench top optimization as well as for the production of small quantities.
The device functions and the various accessories allow for different applications and the coverage of very wide parameter configurations.
UP400St Ultrasonic Homogenizer 400 watts for batch sonication
The UP400St convinces as a powerful and reliable ultrasonic homogenizer: It can be operated continuously 24h/7d under full load and is good for processing up to 400L/h. Generally, the UP400St is used for the sonication of volumes from 5.0 to 4000mL. Due to its robustness and its capability to run 24/7, the UP400St can be also used for the production of smaller quantities. For production processes, the sonication is mostly carried out in a continuous flow-through system with a flow cells and a sonotrode with sealing for the flow cell reactor. In combination with the flow cell FC22K, the material can be sonicated in a continuous flow-through mode, e.g. at a flow rate of 20 to 200mL per minute (the final capacity depends on the application). The stainless steel flow cell is pressurizable up to 5 barg and is equipped with a cooling jacket. By this, inline ultrasonication processes can be simulated in smallest scale.
Video of the Hielscher UP400St - 400 Watts Ultrasonic Homogenizer, a probe type ultrasonicator for intense sample sonication
Video of UP400St - 400 Watts Ultrasonic Homogenizer
UP400St Ultrasonic Homogenizer with Touch-Screen Control
Full Color Touch-Screen
A great enhancement from the operational view is the colored touch-screen. This touch- and stylus-sensitive screen allows for easy handling, whilst the accurate setting of operating parameters and the display of the ultrasound power setting are guaranteed and combined with highest comfort for the operator. The digital control menu is intuitive to use as reduced to the main settings. The amplitude/ power setting and the pulse mode can be adjusted by a colored touch-slider (with 1%, 5% or 10% snap). The user decides, if he prefers the display of amplitude and power as colored bargraphs or numerical display. The screen representation can be changed from regular view mode to BIG NUMBER display mode, characterized by heavy contrast and big font-size for improved visibility.
Browser Remote Control
The UP400St can be controlled using any common browser, such as Internet Explorer, Safari, Firefox, Mozilla, mobile IE/Safari using the new LAN web interface. The LAN connection is a very simple plug-n-play setup and requires no software installation. The ultrasonic device acts as DHCP server/client and requests or assigns an IP automatically. The device can be operated directly from the PC/MAC or using a switch or router. Using an optional pre-configured wireless router, the device can be controlled from most smartphones or tablet computers, e.g. the Apple iPad. Using the port-forwarding of a connected router, you could control your UP400St via internet from any place in the world – your smart-phone or tablet being the remote control.
Built-In Network
Another smart feature of the UP400St is the operation and control via LAN (local area network) which facilitates the operation and allows for high processing flexibility. All information of the sonication process is recorded on SD/USB data card, automatically. An integrated sensor measures the temperature permanently whereas two bright LED lights illuminate the sonicated sample.
Automatic Frequency Tuning
Like all Hielscher ultrasonic devices, the UP400St comes with an intelligent automatic frequency tuning. When the device is switched on, the generator will sense the optimal operational frequency. It will then drive the device at this frequency. That improves the overall energy efficiency and reliability of our ultrasonic devices. All you need to do, is to switch the system on. The generator will perform the frequency tuning automatically in a fraction of a second.
The video is demonstrating ultrasonic dispersion of red color using the UP400St with a S24d 22mm probe.
Ultrasonic Red Color Dispersion using the UP400St
UP400ST sonicator with sound enclosure box SPB-L
The Ultrasonic Processor UP400St in Research and Science
Below you can find a selection of scientific articles featuring the ultrasonic processor UP400St. The articles span from ultrasonic extraction over dispersion to electrochemistry. If you are looking for a specific application and related scientific references, please contact us.
Budniak, A. K., Killilea, N. A., Zelewski, S. J., Sytnyk, M., Kauffmann, Y., Amouyal, Y., Kudrawiec, R., Heiss, W., Lifshitz, E. (2020): Exfoliated CrPS4 with Promising Photoconductivity. Small 2020, 16.
Cold brew tea is rapidly made by sonication. The UP400St extracts flavour and health-promoting compounds from the tea leaves within seconds without applying heat.
Ultrasonic Extraction of Cold Brew Tea using the UP400St.
A great enhancement from the operational view is the colored touch-screen. This touch- and stylus-sensitive screen allows for easy handling, whilst the accurate setting of operating parameters and the display of the ultrasound power setting are guaranteed and combined with highest comfort for the operator. The digital control menu is intuitive to use as reduced to the main settings. The amplitude/ power setting and the pulse mode can be adjusted by a colored touch-slider (with 1%, 5% or 10% snap). The user decides, if he prefers the display of amplitude and power as colored bargraphs or numerical display. The screen representation can be changed from regular view mode to BIG NUMBER display mode, characterized by heavy contrast and big font-size for improved visibility.
